山柰
【气味】辛，温，无毒。
【功效】温中止痛；避秽化浊；醒头去屑。
--摘自《本草纲目》
现代药理研究
山柰富含挥发油、萜类和二芳基庚烷类化合物等有效成分[1-6]。具有很好的抗感染[2]、镇痛[2]、抗炎[3]、抗病毒[4]、抗肿瘤[5]、促消化[6]等作用。具有丰富的药用价值、营养价值和经济价值。
[1]高巧.山柰脂溶性化学成分的研究.北京化工大学,2025.DOI:10.26939/d.cnki.gbhgu.2025.002007.
[2]吴艳婷,陈桂添,时军,等.山柰醋炙前后对甲氧基肉桂酸乙酯含量与抗感染镇痛作用变化研究.广东药学院学报,2016,32(06):679-682+694.DOI:10.16809/j.cnki.1006-8783.2016080503.
[3]王惠玉.山柰酚性成分制备工艺及抗炎活性研究.北京化工大学,2025.DOI:10.26939/d.cnki.gbhgu.2025.002008.
[4]卯玉,方金勇,马婧,等.山柰酚抗HTLV-1病毒侵染及抑制成人T细胞白血病增殖的机制研究.病毒学报,1-13[2025-11-28].https://doi.org/10.13242/j.cnki.bingduxuebao.250144.
[5]杨钊,臧婷,马凯,等.基于PI3K/AKT信号通路研究山柰酚在食管鳞癌中的抗肿瘤作用.医学分子生物学杂志,2024,21(04):354-360.
[6]郑雨雯,梁达均,吴欣颖,等.不同加工方法山柰饮片对功能性消化不良模型大鼠治疗作用研究.广东药科大学学报,2025,41(02):62-68.DOI:10.16809/j.cnki.2096-3653.2024081301.
现代医学中的应用
山柰已被证实是一种抑制癌细胞增殖[1]、促进口腔溃疡加速愈合[2]、舒张血管[3]、抗伪狂犬病病毒[4]、促进伤口愈合[5]、防护酒精导致的胃溃疡[6]等的有效药物，山柰及其制剂在现代医学领域有着广泛的应用前景。
[1]Sasaki Y, Norikura T, Matsui-Yuasa I, Fujii R, Limantara L, Kojima-Yuasa A.Kaempferia galangaL. extract and its main component, ethylp-methoxycinnamate, inhibit the proliferation of Ehrlich ascites tumor cells by suppressing TFAM expression.Heliyon. 2023;9(6):e17588. Published 2023 Jun 23. doi:10.1016/j.heliyon.2023.e17588
[2]Wahyuni IS, Diina TR, Salsabila AS, et al.Kaempferia galangaL. alleviates the expression of COX-2 and NF-kappaB-p65 in the oral mucosa ulcer of Wistar rats and exhibits no irritation toward the vascular membrane of chicken eggs and the skin of albino rabbits.Heliyon. 2024;10(16):e35827. Published 2024 Aug 9. doi:10.1016/j.heliyon.2024.e35827
[3]Srivastava N, Mishra S, Iqbal H, Chanda D, Shanker K. Standardization of Kaempferia galanga L. rhizome and vasorelaxation effect of its key metabolite ethyl p-methoxycinnamate.J Ethnopharmacol. 2021;271:113911. doi:10.1016/j.jep.2021.113911
[4]Chen X, Wang R, Hu H, et al. Antiviral effect of an extract from Kaempferia galanga L. rhizome in mice infected with pseudorabies virus.J Virol Methods. 2022;307:114573. doi:10.1016/j.jviromet.2022.114573
[5]Sudsai T, Tungcharoen P, Tewtrakul S. Wound healing properties of pharmaceutical gel containing isopimarane diterpene isolated from Kaempferia galanga L.J Ethnopharmacol. 2022;289:115052. doi:10.1016/j.jep.2022.115052
[6]Liu H, Chen Y, Hu Y, et al. Protective effects of an alcoholic extract of Kaempferia galanga L. rhizome on ethanol-induced gastric ulcer in mice.J Ethnopharmacol. 2024;325:117845. doi:10.1016/j.jep.2024.117845黎怡生（久健本康编辑部）
